PI3K inhibitor PF-4989216, Purity ≥98%

Synonym: 1276553-09-3; PF4989216; PF 4989216; PI3K inhibitor

CAS Number: 1276553-09-3
Compound CID: 51033720

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PF-4989216, soluble in DMSO and warmed ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets p110α, p110β, p110δ, p110γ, and Vps34.

Molecular Weight

380.4

Molecular Formula

C₁₈H₁₃FN₆OS

Targets

p110α: 2 nM; p110β: 142 nM; p110δ: 1 nM; p110γ: 65 nM; Vps34: 110 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 66 mg/mL (173.49 mM); Water: Insoluble; Warmed ethanol: 6 mg/mL (15.77 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

PF-4989216 is utilized to investigate PI3Kγ signaling in cancer and inflammation.

Storage

Store at -20ºC.