Properties
Description
PI-103, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets p110β, p110γ, DNA-PK, mTOR, p110α, and p110γ.
Molecular Formula
C19H16N4O3
Targets
p110β: 3 nM; p110γ: 3 nM; DNA-PK: 23 nM; mTOR: 30 nM; p110α: 2 nM; p110γ: 15 nM
Solubility
DMSO: 22 mg/mL (63.15 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PI-103 is utilized to investigate the dual inhibition of PI3K and mTOR pathways in cancer and cellular biology studies.
