PI3K inhibitor PI-3065, Purity ≥98%

Synonym: 955977-50-1; PI3065; PI 3065; PI3K inhibitor

CAS Number: 955977-50-1
Compound CID: 24937012

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PI-3065, soluble in warmed DMSO and insoluble in water and ethanol, is a potent compound that inhibits PI3 kinase activity. It targets p110α, p110β, DNA-PK, p110δ, p110γ, and mTOR.

Molecular Weight

506.64

Molecular Formula

C₂₇H₃₁FN₆OS

Targets

p110α: 2299 nM; p110β: 1078 nM; DNA-PK: >10000 nM; p110δ: 15 nM; p110γ: 27542 nM; mTOR: 9082 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 50 mg/mL (98.68 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

PI-3065 targets PI3Kα, used to study signaling pathways in cancer and other diseases.