Properties
Description
PIK-293, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets p110α, p110β, p110δ, and p110γ.
Molecular Formula
C22H19N7O
Targets
p110α: 100 μM; p110β: 25 μM; p110δ: 0.24 μM; p110γ: 10 μM
Solubility
DMSO: 75 mg/mL (188.71 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PIK-293 targets PI3K for studying its role in oncogenic signaling.