PI3K inhibitor PIK-75 hydrochloride, Purity ≥98%

Synonym: 372196-77-5; PIK75; PI3K inhibitor

CAS Number: 372196-77-5
Compound CID: 45265864

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PIK-75 hydrochloride, soluble in warmed DMSO and insoluble in water and ethanol, is a potent compound that inhibits PI3 kinase activity. It targets DNA-PK, p110α, p110β, p110δ, and p110γ.

Molecular Weight

488.7

Molecular Formula

C₁₆H₁₄BrN₅O₄S.HCl

Targets

DNA-PK: 2 nM; p110α: 5.8 nM; p110β: 1.3 nM; p110δ: 0.51 μM; p110γ: 76 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 4 mg/mL (8.18 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

PIK-75 hydrochloride is applied to investigate PI3Kα inhibition in cancer and other diseases.