PI3K inhibitor PIK-III, Purity ≥98%

Synonym: 1383716-40-2; VPS34-IN2; PI3K inhibitor

CAS Number: 1383716-40-2
Compound CID: 67983123

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PIK-III, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kδ, PI3Kγ, mTOR, PI3Kα, PI3Kβ, PI3Kβ, and Vps34.

Molecular Weight

319.36

Molecular Formula

C₁₇H₁₇N₇

Targets

PI3Kδ: 1.2 μM; PI3Kγ: 3.04 μM; mTOR: >9.1 μM; PI3Kα: 3.96 μM; PI3Kβ: >9.1 μM; PI3Kβ: 4.43 μM; Vps34: 0.018 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 56 mg/mL (175.34 mM); Water: Insoluble; Ethanol: 56 mg/mL (175.34 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

PIK-III serves as an inhibitor of autophagic PI3K VPS34, useful for studying autophagy and cellular trafficking.