PI3K inhibitor PKI-587, Purity ≥98%

Synonym: 1197160-78-3; KI587; Gedatolisib; PI3K inhibitor

CAS Number: 1197160-78-3
Compound CID: 44516953

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PKI-587, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR, PI3Kα, and PI3Kγ.

Molecular Weight

615.7

Molecular Formula

C₃₂H₄₁N₉O₄

Targets

mTOR: 1.6 nM; PI3Kα: 0.4 nM; PI3Kγ: 5.4 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 2 mg/mL (3.24 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

PKI-587 can be used to investigate the effects of dual PI3K/mTOR inhibition in cancer research.