Properties
Description
PQR-530 is a potent compound that inhibits PI3 kinase activity. It targets mTOR, PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ, and PI3KC2β.
Molecular Formula
C18H23F2N7O2
Targets
mTOR: 0.33 nM (Kd); PI3Kα: 0.84 nM (Kd); PI3Kβ: 6.1 nM (Kd); PI3Kδ: 11 nM (Kd); PI3Kγ: 10 nM (Kd); PI3KC2β: 100 nM (Kd)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PQR-530 can be used to study the inhibition of mTORC1 and mTORC2 in cancer metabolism research.
