PI3K inhibitor Rigosertib sodium, Purity ≥98%

Synonym: 592542-60-4; ON-01910 sodium; ON01910; ON 01910; PI3K inhibitor

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Rigosertib sodium is a potent compound that inhibits PI3 kinase activity. It targets BCR-ABL, Cdk1, Flt1, Fyn, PDGFR, PLK1, PLK2, and Src.

Molecular Weight

473.47

Molecular Formula

C₂₁H₂₄NNaO₈S

Targets

BCR-ABL: 32 nM; Cdk1: 260 nM; Flt1: 42 nM; Fyn: 182 nM; PDGFR: 18 nM; PLK1: 9 nM; PLK2: 260 nM; Src: 155 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

Rigosertib sodium is used to study its inhibition of PI3K and its potential anti-cancer effects, especially in myelodysplastic syndromes.