PI3K inhibitor SAR245409, Purity ≥98%

Synonym: 934493-76-2; Voxtalisib; XL765; SAR 245409; SAR-245409; XL 765; XL-765; PI3K inhibitor

CAS Number: 934493-76-2
Compound CID: 16123056

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SAR245409, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα, PI3Kδ, DNA-PK, mTOR, PI3Kβ, and PI3Kγ.

Molecular Weight

270.29

Molecular Formula

C₁₃H₁₄N₆O

Targets

PI3Kα: 39 nM; PI3Kδ: 43 nM; DNA-PK: 150 nM; mTOR: 157 nM; PI3Kβ: 113 nM; PI3Kγ: 9 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 53 mg/mL (196.08 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

SAR245409 can be used to explore dual inhibition of PI3K/mTOR pathways in oncology research.