PI3K inhibitor SAR405, Purity ≥98%

Synonym: 1523406-39-4; SAR 405; SAR-405; PI3K inhibitor

CAS Number: 1523406-39-4
Compound CID: 72709209

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SAR405, soluble in warmed DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets Autophagy, Vps34, and Vps34.

Molecular Weight

443.85

Molecular Formula

C₁₉H₂₁ClF₃N₅O₂

Targets

Autophagy; Vps34: 1.2 nM; Vps34: 1.5 nM (Kd)

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 76 mg/mL (171.22 mM); Water: Insoluble; Ethanol: 76 mg/mL (171.22 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

SAR405 can be employed to investigate the inhibition of class III PI3K and its impact on autophagy and cellular trafficking.