PI3K inhibitor SAR405, Purity ≥98%

Synonym: 1523406-39-4; SAR 405; SAR-405; PI3K inhibitor

CAS Number: 1523406-39-4
Compound CID: 72709209

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SAR405, soluble in warmed DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets Autophagy, Vps34, and Vps34.

Molecular Weight

443.85

Molecular Formula

C₁₉H₂₁ClF₃N₅O₂

Targets

Autophagy; Vps34: 1.2 nM; Vps34: 1.5 nM (Kd)

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 76 mg/mL (171.22 mM); Water: Insoluble; Ethanol: 76 mg/mL (171.22 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

SAR405 can be employed to investigate the inhibition of class III PI3K and its impact on autophagy and cellular trafficking.

Storage

Store at -20ºC.