Properties
Description
SF2523, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets BRD4 (BD1), DNA-PK, mTOR, PI3Kα, and PI3Kγ.
Molecular Formula
C19H17NO5S
Targets
BRD4 (BD1): 241 nM; DNA-PK: 9 nM; mTOR: 280 nM; PI3Kα: 34 nM; PI3Kγ: 158 nM
Solubility
DMSO: 29 mg/mL (78.08 mM); Water: Insoluble; Ethanol: 7 mg/mL (18.84 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
SF2523 can be employed to study the inhibition of PI3K and the downstream effects on cancer cell survival and proliferation.
