PI3K inhibitor SF2523, Purity ≥98%

Synonym: 1174428-47-7; SF 2523; SF-2523; PI3K inhibitor

CAS Number: 1174428-47-7
Compound CID: 44180156

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SF2523, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets BRD4 (BD1), DNA-PK, mTOR, PI3Kα, and PI3Kγ.

Molecular Weight

371.41

Molecular Formula

C₁₉H₁₇NO₅S

Targets

BRD4 (BD1): 241 nM; DNA-PK: 9 nM; mTOR: 280 nM; PI3Kα: 34 nM; PI3Kγ: 158 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 29 mg/mL (78.08 mM); Water: Insoluble; Ethanol: 7 mg/mL (18.84 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

SF2523 can be employed to study the inhibition of PI3K and the downstream effects on cancer cell survival and proliferation.

Storage

Store at -20ºC.