PI3K inhibitor SF2523, Purity ≥98%

Synonym: 1174428-47-7; SF 2523; SF-2523; PI3K inhibitor

CAS Number: 1174428-47-7
Compound CID: 44180156

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

SF2523, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets BRD4 (BD1), DNA-PK, mTOR, PI3Kα, and PI3Kγ.

Molecular Weight

371.41

Molecular Formula

C₁₉H₁₇NO₅S

Targets

BRD4 (BD1): 241 nM; DNA-PK: 9 nM; mTOR: 280 nM; PI3Kα: 34 nM; PI3Kγ: 158 nM

Form

Lyophilized powder

Purity

Solubility

DMSO: 29 mg/mL (78.08 mM); Water: Insoluble; Ethanol: 7 mg/mL (18.84 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

SF2523 can be employed to study the inhibition of PI3K and the downstream effects on cancer cell survival and proliferation.