PI3K inhibitor TGR-1202 hydrochloride, Purity ≥98%

Synonym: 1532533-78-0; RP5264 hydrochloride; TGR1202 hydrochloride; TGR 1202 hydrochloride; RP-5264 hydrochloride; RP 5264 hydrochloride; PI3K inhibitor

CAS Number: 1532533-78-0
Compound CID: 90030289

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TGR-1202 hydrochloride is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα, PI3Kβ, PI3Kδ, PI3Kδ, and PI3Kγ.

Molecular Weight

608.01

Molecular Formula

C₃₁H₂₅ClF₃N₅O₃

Targets

PI3Kα: >10000 nM (Kd); PI3Kβ: >10000 nM (Kd); PI3Kδ: 22.2 nM (EC₅₀); PI3Kδ: 6.2 nM (Kd); PI3Kγ: 1400 nM (Kd)

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

TGR-1202 hydrochloride is applied to study the selective inhibition of PI3Kδ and its therapeutic potential in hematological cancers.

Storage

Store at -20ºC.