Properties
Description
VS-5584, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Formula
C17H22N8O
Targets
mTOR: 3.4 nM; PI3Kα: 2.6 nM; PI3Kβ: 21 nM; PI3Kδ: 2.7 nM; PI3Kγ: 3.0 nM
Solubility
DMSO: 70 mg/mL (197.51 mM); Water: Insoluble; Ethanol: 3 mg/mL (8.46 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
VS-5584 can be used to study the dual inhibition of PI3K/mTOR pathways in cancer research.
