PI3K inhibitor XL-147, Purity ≥98%

Synonym: 934526-89-3; SAR245408; XL 147; XL147; SAR-245408; SAR 245408; Pilaralisib; PI3K inhibitor

CAS Number: 934526-89-3
Compound CID: 56599306

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

XL-147, soluble in warmed DMSO and insoluble in water and ethanol, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.

Molecular Weight

541.02

Molecular Formula

C₂₅H₂₅ClN₆O₄S

Targets

PI3Kα: 39 nM; PI3Kβ: 36 nM; PI3Kδ: 36 nM; PI3Kγ: 23 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 92 mg/mL (170.04 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

XL-147 is utilized to understand the inhibition of PI3K and its downstream effects in cancer therapeutics.