Properties
Description
YM201636, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets p110α and PIKfyve.
Molecular Formula
C25H21N7O3
Targets
p110α: 3.3 μM; PIKfyve: 33 μM
Solubility
DMSO: 31 mg/mL (66.3 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
YM201636 is used to research the inhibition of PIKfyve and its effects on cellular trafficking and endocytosis.