Properties
Description
YM201636, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets p110α and PIKfyve.
Molecular Formula
C25H21N7O3
Targets
p110α: 3.3 μM; PIKfyve: 33 μM
Solubility
DMSO: 31 mg/mL (66.3 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
YM201636 is used to research the inhibition of PIKfyve and its effects on cellular trafficking and endocytosis.