PI3K inhibitor ZSTK474, Purity ≥98%

Synonym: 475110-96-4; ZSTK474; ZSTK-474; 4,4'-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine; ZSTK 474; PI3K inhibitor

CAS Number: 475110-96-4
Compound CID: 11647372

Product Size

10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ZSTK474, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets PI3K, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.

Molecular Weight

417.4

Molecular Formula

C₁₉H₂₁F₂N₇O₂

Targets

PI3K: 37 nM; PI3Kα: 16 nM; PI3Kβ: 44 nM; PI3Kδ: 4.6 nM; PI3Kγ: 49 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 20 mg/mL (47.91 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

ZSTK474 can be used to investigate the role of PI3K in cancer by inhibiting its activity.