PI3K inhibitor ZSTK474, Purity ≥98%

Synonym: 475110-96-4; ZSTK474; ZSTK-474; 4,4'-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine; ZSTK 474; PI3K inhibitor

CAS Number: 475110-96-4
Compound CID: 11647372

Product Size

10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ZSTK474, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets PI3K, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.

Molecular Weight

417.4

Molecular Formula

C₁₉H₂₁F₂N₇O₂

Targets

PI3K: 37 nM; PI3Kα: 16 nM; PI3Kβ: 44 nM; PI3Kδ: 4.6 nM; PI3Kγ: 49 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 20 mg/mL (47.91 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

ZSTK474 can be used to investigate the role of PI3K in cancer by inhibiting its activity.

Storage

Store at -20ºC.