Pim inhibitor AZD1208, Purity ≥98%

Synonym: AZD1208; 1204144-28-4; AZD-1208; (R,Z)-5-((2-(3-Aminopiperidin-1-yl)-[1,1'-biphenyl]-3-yl)methylene)thiazolidine-2,4-dione; S98NFM1378; UNII-S98NFM1378; (5Z)-5-({2-[(3R)-3-Aminopiperidin-1-yl]-3-phenylphenyl}methylidene)-1,3-thiazolidine-2,4-dione; Pim inhibitor

MDL: MFCD25976757
CAS Number: 1204144-28-4
Compound CID: 58423153

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZD1208, soluble in warmed DMSO and insoluble in water and ethanol, is a selective and ATP-competitive Pim kinase inhibitor. It targets Pim1, Pim2, and Pim3.

Molecular Weight

379.48

Molecular Formula

C₂₁H₂₁N₃O₂S

Targets

Pim1: 0.4 nM; Pim2: 5 nM; Pim3: 1.9 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 70 mg/mL (184.45 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

AZD1208 can be utilized to investigate PIM kinase inhibition, focusing on its anti-cancer properties.