Pim inhibitor AZD1208, Purity ≥98%

Synonym: AZD1208; 1204144-28-4; AZD-1208; (R,Z)-5-((2-(3-Aminopiperidin-1-yl)-[1,1'-biphenyl]-3-yl)methylene)thiazolidine-2,4-dione; S98NFM1378; UNII-S98NFM1378; (5Z)-5-({2-[(3R)-3-Aminopiperidin-1-yl]-3-phenylphenyl}methylidene)-1,3-thiazolidine-2,4-dione; Pim inhibitor

MDL: MFCD25976757
CAS Number: 1204144-28-4
Compound CID: 58423153

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZD1208, soluble in warmed DMSO and insoluble in water and ethanol, is a selective and ATP-competitive Pim kinase inhibitor. It targets Pim1, Pim2, and Pim3.

Molecular Weight

379.48

Molecular Formula

C₂₁H₂₁N₃O₂S

Targets

Pim1: 0.4 nM; Pim2: 5 nM; Pim3: 1.9 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 70 mg/mL (184.45 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AZD1208 can be utilized to investigate PIM kinase inhibition, focusing on its anti-cancer properties.

Storage

Store at -20ºC.