Pim inhibitor CX-6258 HCl, Purity ≥98%

Synonym: CX-6258 HCl; 1353859-00-3; CX-6258 Hydrochloride; CX-6258 (hydrochloride); (E)-5-Chloro-3-((5-(3-(4-methyl-1,4-diazepane-1-carbonyl)phenyl)furan-2-yl)methylene)indolin-2-one hydrochloride; (3E)-5-Chloro-3-[[5-[3-[(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)carbonyl]phenyl]-2-furanyl]methylene]-1,3-dihydro-2H-indol-2-one hydrochloride; Pim-Kinase Inhibitor X; Pim inhibitor

CAS Number: 1353859-00-3
Compound CID: 72201040

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CX-6258 HCl, soluble in warmed DMSO, warmed water and warmed ethanol, is a selective and ATP-competitive Pim kinase inhibitor. It targets Pim1, Pim2, and Pim3.

Molecular Weight

498.4

Molecular Formula

C₂₆H₂₄ClN₃O₃.HCl

Targets

Pim1: 5 nM; Pim2: 25 nM; Pim3: 16 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 55 mg/mL (110.35 mM); Warmed water: 86 mg/mL (172.55 mM); Warmed ethanol: 55 mg/mL (110.35 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

CX-6258 HCl can be employed to explore the inhibition of PIM1 kinase in oncology research.