Pim inhibitor INCB053914 phosphate, Purity ≥98%

Synonym: PIM inhibitor 1 phosphate; 2088852-47-3; INCB053914 phosphate; Uzansertib (phosphate); N-[(7R)-4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperidin-1-yl]-7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridin-3-yl]-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide; phosphoric acid; Uzansertib phosphate; Pim inhibitor

CAS Number: 2088852-47-3
Compound CID: 126673672

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

INCB053914 phosphate, soluble in DMSO, is a selective and ATP-competitive Pim kinase inhibitor. It targets PIM1, PIM2, and PIM3.

Molecular Weight

611.51

Molecular Formula

C₂₆H₂₉F₃N₅O₇P

Targets

PIM1: 0.24 nM; PIM2: 30 nM; PIM3: 0.12 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 48 mg/mL (78.49 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

INCB053914 phosphate can be investigated for its role as a selective PIM kinase inhibitor in oncology.

Storage

Store at -20ºC.