Pim inhibitor SGI-1776 (free base), Purity ≥98%

Synonym: SGI-1776; 1025065-69-3; SGI-1776 free base; N-[(1-Methylpiperidin-4-yl)methyl]-3-[3-(trifluoromethoxy)phenyl]imidazo[1,2-b]pyridazin-6-amine; SGI1776; N-((1-Methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine; Pim inhibitor

MDL: MFCD16659064
CAS Number: 1025065-69-3
Compound CID: 24795070

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SGI-1776 (free base), soluble in DMSO and ethanol and insoluble in water, is a selective and ATP-competitive Pim kinase inhibitor.

Molecular Weight

405.4

Molecular Formula

C₂₀H₂₂F₃N₅O

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 70 mg/mL (172.66 mM); Water: Insoluble; Ethanol: 70 mg/mL (172.66 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

SGI-1776 (free base) can be used to investigate the potential anti-cancer effects through PIM kinase inhibition.