Pim inhibitor TCS PIM-1 4a, Purity ≥98%

Synonym: SMI-4a; 438190-29-5; SMI 4a; TCS PIM-1 4a; (Z)-SMI-4a; (5Z)-5-[3-(Trifluoromethyl)benzylidene]-1,3-thiazolidine-2,4-dione; (Z)-5-(3-(Trifluoromethyl)benzylidene)thiazolidine-2,4-dione; Pim inhibitor

MDL: MFCD01152003
CAS Number: 438190-29-5
Compound CID: 1361334

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TCS PIM-1 4a, soluble in DMSO and ethanol and insoluble in water, is a selective and ATP-competitive Pim kinase inhibitor. It targets Pim1.

Molecular Weight

273.23

Molecular Formula

C₁₁H₆F₃NO₂S

Targets

Pim1: 17 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 47 mg/mL (172.01 mM); Water: Insoluble; Ethanol: 28 mg/mL (102.47 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

TCS PIM-1 4a can be employed to explore PIM1 kinase inhibition in cancer research.