Properties
Description
Pimavanserin, soluble in DMSO, ethanol and water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT2A.
Molecular Formula
C50H68F2N6O4·C4H6O6
Targets
5-HT2A: 8.73 (pIC50)
Solubility
DMSO: 95 mg/mL (94.51 mM); Water: 95 mg/mL (94.51 mM); Ethanol: 95 mg/mL (94.51 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Pimavanserin can be used for its ability to mitigate hallucinations and delusions without worsening motor function in individuals with PDP.
Storage
Store at -20°C, and keep desiccated.
