Pirfenidone

Synonym: 53179-13-8; AMR69; Esbriet; Deskar

CAS Number: 53179-13-8
PubChem CID: 40632

Product Size

100 mg; 200 mg; 500 mg; 1 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Pirfenidone, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets TGF-β (cell-free assay).

Molecular Weight

185.22

Molecular Formula

C₁₂H₁₁NO

Targets

TGF-β

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 37 mg/mL (199.76 mM); Water: insoluble; Ethanol: 37 mg/mL (199.76 mM)

Applications

Pirfenidone can be used in the research of chronic fibrosing ILDs with a progressive phenotype, beyond IPF and SSc-ILD.