Properties
Description
Pirfenidone, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets TGF-β (cell-free assay).
Molecular Formula
C12H11NO
Solubility
DMSO: 37 mg/mL (199.76 mM); Water: insoluble; Ethanol: 37 mg/mL (199.76 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Pirfenidone can be used in the research of chronic fibrosing ILDs with a progressive phenotype, beyond IPF and SSc-ILD.
Storage
Store at -20℃, and keep desiccated.
