PKC inhibitor H 89 2HCl, Purity ≥98%

Synonym: h-89; 127243-85-0; H 89; N-(2-(4-Bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide; N-[2-[[(E)-3-(4-bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5-sulfonamide; PKC inhibitor

CAS Number: 127243-85-0, 130964-39-5
Compound CID: 449241

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

H 89 2HCl, soluble in DMSO and water and insoluble in ethanol, acts as an ATP-competitive PKC inhibitor.

Molecular Weight

519.3

Molecular Formula

C₂₀H₂₀BrN₃O₂S.2HCl

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 96 mg/mL (184.86 mM); Water: 6 mg/mL (11.55 mM); Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

H 89 2HCl can be used to examine the inhibition of protein kinase A (PKA) in the regulation of cellular metabolism and gene expression.

Storage

Store at -20ºC.