PKC inhibitor LY317615, Purity ≥98%

Synonym: Enzastaurin; 170364-57-5; LY317615; Enzastaurin (LY317615); 3-(1-Methyl-1H-indol-3-yl)-4-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-1H-indol-3-yl)-1H-pyrrole-2,5-dione; LY-317615; 3-(1-Methylindol-3-yl)-4-[1-[1-(pyridin-2-ylmethyl)piperidin-4-yl]indol-3-yl]pyrrole-2,5-dione; PKC inhibitor

MDL: MFCD11040980
CAS Number: 170364-57-5
Compound CID: 176167

Product Size

10 mg; 25 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

LY317615, soluble in DMSO and insoluble in ethanol and water, acts as an ATP-competitive PKC inhibitor. It targets PKCα, PKCβ, PKCε, and PKCγ.

Molecular Weight

515.6

Molecular Formula

C₃₂H₂₉N₅O₂

Targets

PKCα: 39 nM; PKCβ: 6 nM; PKCε: 110 nM; PKCγ: 83 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 29 mg/mL (56.24 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

LY317615 can be used to study its inhibitory effects on PKCβ and its potential therapeutic applications in diabetes-related complications and cancer.