PKC inhibitor LY317615, Purity ≥98%

Synonym: Enzastaurin; 170364-57-5; LY317615; Enzastaurin (LY317615); 3-(1-Methyl-1H-indol-3-yl)-4-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-1H-indol-3-yl)-1H-pyrrole-2,5-dione; LY-317615; 3-(1-Methylindol-3-yl)-4-[1-[1-(pyridin-2-ylmethyl)piperidin-4-yl]indol-3-yl]pyrrole-2,5-dione; PKC inhibitor

MDL: MFCD11040980
CAS Number: 170364-57-5
Compound CID: 176167

Product Size

10 mg; 25 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

LY317615, soluble in DMSO and insoluble in ethanol and water, acts as an ATP-competitive PKC inhibitor. It targets PKCα, PKCβ, PKCε, and PKCγ.

Molecular Weight

515.6

Molecular Formula

C₃₂H₂₉N₅O₂

Targets

PKCα: 39 nM; PKCβ: 6 nM; PKCε: 110 nM; PKCγ: 83 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 29 mg/mL (56.24 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

LY317615 can be used to study its inhibitory effects on PKCβ and its potential therapeutic applications in diabetes-related complications and cancer.

Storage

Store at -20ºC.