PKC-theta inhibitor 1

Synonym: 1160501-81-4; HY-126328

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PKC-theta inhibitor 1 blocks the function of Smad proteins in the TGF-β signaling pathway. It targets IL-2 production, PKCα, PKCδ, and PKCθ.

Molecular Weight

348.32

Molecular Formula

C₁₇H₁₅F₃N₄O

Targets

IL-2 production: 0.19 μM; PKCα: 1020 μM; PKCδ: 392 μM; PKCθ: 6 nM

Form

Lyophilized powder

Purity

>98%

Applications

PKC-theta inhibitor 1 can be used to enhance the anti-tumor activity of T cells, leading to improved efficacy of cancer immunotherapy approaches.