PKD inhibitor CRT-0066101, Purity ≥98%

Synonym: 1883545-60-5; CRT0066101; CRT0066101 Dihydrochloride; (R)-2-(4-((2-Aminobutyl)amino)pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol dihydrochloride; PKD inhibitor

CAS Number: 1883545-60-5
Compound CID: 136664697

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CRT-0066101, soluble in warmed DMSO, water and warmed ethanol, typically functions by binding to the ATP-binding site of the kinase domain, thereby preventing the phosphorylation and activation of downstream substrates.

Molecular Weight

411.33

Molecular Formula

C₁₈H₂₂N₆O.2HCl

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 25 mg/mL (60.77 mM); Water: 80 mg/mL (194.49 mM); Warmed ethanol: 2 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

CRT-0066101 can be used to study the inhibition of protein kinase D (PKD) signaling pathways.

Storage

Store at -20ºC.