Potassium channel inhibitor TAK-438, Purity ≥98%

Synonym: 1260141-27-2; Potassium channel inhibitor; TAK438

MDL: MFCD18633280
CAS Number: 1260141-27-2
Compound CID: 45375887

Product Size

2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TAK-438, soluble in DMSO and insoluble in ethanol and water, modulates the activity of potassium channels, impacting numerous physiological processes such as nerve signal transmission, muscle contraction, and heart rhythm regulation. It targets H+/K+-ATPase.

Molecular Weight

461.5

Molecular Formula

C₂₁H₂₀FN₃O₆S

Targets

H+/K+-ATPase: 19 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 58 mg/mL (125.68 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

TAK-438 is investigated as a potassium channel inhibitor; although primarily known as a potassium-competitive acid blocker (P-CAB), it serves in gastrointestinal research focusing on acid-related diseases.