Potassium channel inhibitor TRAM-34, Purity ≥98%

Synonym: 289905-88-0; Potassium channel inhibitor; TRAM34; TRAM 34

MDL: MFCD09842562
CAS Number: 289905-88-0
Compound CID: 656734

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TRAM-34, soluble in DMSO and insoluble in ethanol and water, modulates the activity of potassium channels, impacting numerous physiological processes such as nerve signal transmission, muscle contraction, and heart rhythm regulation. It targets IKCa1 (KCa3.1).

Molecular Weight

344.84

Molecular Formula

C₂₂H₁₇ClN₂

Targets

IKCa1 (KCa3.1): 20 nM (Kd)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 0.36 mg/mL (1.04 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

TRAM-34 inhibits calcium-activated potassium channels and is used in research to investigate immune responses and cancer.