PPAR inhibitor, BMS-687453, Purity ≥98%

Synonym: 1000998-59-3; BMS687453; BMS 687453; 2-[[3-[[2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy]phenyl]methyl-methoxycarbonylamino]acetic acid

MDL: MFCD18251482
CAS Number: 1000998-59-3
Compound CID: 16725047

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BMS-687453, soluble in DMSO and ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PPAR. It targets the PPARα.

Molecular Weight

444.86

Molecular Formula

C₂₂H₂₁ClN₂O₆

Targets

PPARα: 260 nM (IC₅₀, human PPARα)

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 80 mg/mL (179.83 mM); Water: insoluble; Ethanol: 80 mg/mL

Applications

BMS-687453 is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of type 2 diabetes by improving insulin sensitivity and glucose homeostasis.