PPAR inhibitor, Elafibranor, Purity ≥98%

Synonym: 923978-27-2; GFT505; GFT-505; GFT 505; 2-[2,6-Dimethyl-4-[(E)-3-(4-methylsulfanylphenyl)-3-oxoprop-1-enyl]phenoxy]-2-methylpropanoic acid

MDL: MFCD27987940
CAS Number: 923978-27-2
Compound CID: 9864881

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Elafibranor, soluble in DMSO and ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PPAR. It targets the PPAR-α and PPAR-δ.

Molecular Weight

384.49

Molecular Formula

C₂₂H₂₄O₄S

Targets

PPAR-α: 45 nM (EC₅₀); PPAR-δ: 175 nM (EC₅₀)

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 74 mg/mL (192.46 mM); Water: insoluble; Ethanol: 74 mg/mL (192.46 mM)

Applications

Elafibranor is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of non-alcoholic steatohepatitis (NASH) and dyslipidemia.