Properties
Description
GW 9662, soluble in DMSO and insoluble in water and ethanol, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PPAR. It targets the PPARα (cell-free assay), PPARδ (cell-free assay), and PPARγ (cell-free assay).
Molecular Formula
C13H9N2O3Cl
Targets
PPARα (Cell-free assay): 32 nM; PPARδ (Cell-free assay): 2 μM; PPARγ (Cell-free assay): 3.3 nM
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 48 mg/mL (173.48 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + corn oil, 8 mg/mL
Applications
GW 9662 is a metabolism inhibitor that plays a key role in research to investigate the effects of inhibiting PPAR纬, which is involved in glucose and lipid metabolism, and to study its role in diseases like diabetes and cancer.
