PPAR inhibitor, GW0742, Purity ≥98%

Synonym: 317318-84-6; GW-0742; GW 0742; 2-[4-[[2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid

MDL: MFCD07369423
CAS Number: 317318-84-6
Compound CID: 9934458

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

GW0742, soluble in DMSO and ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PPAR. It targets the PPARδ.

Molecular Weight

471.49

Molecular Formula

C₂₁H₁₇F₄NO₃S₂

Targets

PPARδ: 1 nM

Form

Lyophilized powder

Purity

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 86 mg/mL (182.39 mM); Water: insoluble; Ethanol: 40 mg/mL (84.84 mM); In vivo: 2% DMSO + 40% PEG 300 + 2% Tween 80 + ddH₂O, 2 mg/mL

Applications

GW0742 is a metabolism inhibitor that plays a key role in research to explore the effects of activating PPAR未 on metabolism, inflammation, and potential therapeutic benefits for conditions such as obesity and type 2 diabetes.