PPAR inhibitor, NXT629, Purity ≥98%

Synonym: 1454925-59-7; NXT 629; NXT-629; N-[6-[4-[3-[1-[(4-tert-butylphenyl)methyl]-4-ethyl-5-oxo-1,2,4-triazol-3-yl]propyl]phenyl]pyridin-3-yl]benzenesulfonamide

CAS Number: 1454925-59-7
Compound CID: 71721539

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NXT629 is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PPAR. It targets the ERβ, GR, hPPARα, and hPPARδ.

Molecular Weight

609.78

Molecular Formula

C₃₅H₃₉N₅O₃S

Targets

ERβ: 15.2 μM (IC₅₀); GR: 32.5 μM (IC₅₀); hPPARα: 77 nM (IC₅₀); hPPARδ: 6 μM (IC₅₀)

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Applications

NXT629 is a metabolism inhibitor that plays a key role in research to understand the role of PPARγ in metabolic diseases and to explore its potential as a target for treating conditions such as obesity and diabetes.