PPAR inhibitor, Pioglitazone hydrochloride, Purity ≥98%

Synonym: 112529-15-4; U 72107A; U72107A; U-72107A; AD 4833; AD-4833; AD4833; 5-[[4-[2-(5-Ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione; hydrochloride

MDL: MFCD04975446
CAS Number: 112529-15-4
Compound CID: 60560

Product Size

100 mg; 500 mg; 1000 mg; 2000 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Pioglitazone hydrochloride, soluble in DMSO and ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PPAR. It targets the PPARα, PPARδ, and PPARγ.

Molecular Weight

392.9

Molecular Formula

C₁₉H₂₁ClN₂O₃S

Targets

PPARα: 0.93 μM (EC₅₀, human PPARα); PPARδ: 0.01 μM (EC₅₀, human PPARδ); PPARγ: 43 μM (EC₅₀, human PPARγ)

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 70 mg/mL (178.15 mM); Water: insoluble; Ethanol: 4 mg/mL (10.18 mM)

Applications

Pioglitazone hydrochloride is a metabolism inhibitor that can be used for its beneficial effects on lipid profiles.