PPAR inhibitor, Pirinixic acid, Purity ≥98%

Synonym: 50892-23-4; WY 14643; Wyeth 14643; Wy 14643; WY-14643; WY14643; 2-[4-Chloro-6-(2,3-dimethylanilino)pyrimidin-2-yl]sulfanylacetic acid

MDL: MFCD00191335
CAS Number: 50892-23-4
Compound CID: 5694

Product Size

50 mg; 100 mg; 250 mg; 500 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Pirinixic acid, soluble in DMSO and ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PPAR. It targets the PPARα.

Molecular Weight

323.8

Molecular Formula

C₁₄H₁₄ClN₃O₂S

Targets

PPARα: 1.5 μM (EC₅₀)

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 63 mg/mL (194.56 mM); Water: insoluble; Ethanol: 51 mg/mL (157.5 mM); In vivo: 30% PEG400 + 2% Tween 80 + PBS, 4 mg/mL

Applications

Pirinixic acid is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of dyslipidemia and metabolic disorders.