Unlocking Potential in Pharmaceuticals: Precision Pregelatinized Hydroxypropyl Starch Analysis

CD BioGlyco provides an analysis service for pregelatinized hydroxypropyl starch, a versatile derivative used in pharmaceuticals, food, and cosmetics. Through pre-gelatinization, achieved by heat and drying, the starch's properties are modified, with hydroxypropyl groups enhancing solubility and stability. In pharmaceuticals, it acts as an excipient in tablets, aiding in binding, disintegration, and controlled release. In food, it thickens and stabilizes products like soups and sauces, improving texture. In cosmetics, it serves as a binder and thickener in creams and lotions. Our comprehensive and reliable analysis service ensures quality control for hydroxypropyl starch samples, complemented by various other Pharmaceutical Excipient Analysis Services for client needs.

At CD BioGlyco, our pregelatinized hydroxypropyl starch analysis service is designed to deliver reliable and professional results through comprehensive testing methodologies. We meticulously conduct identification, specific, and content tests to ensure accurate and detailed analysis.

• Identification test

Our identification test aims to confirm the presence and specific identity of pregelatinized hydroxypropyl starch in the sample. This process utilizes advanced analytical techniques, including fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance (NMR) spectroscopy. FTIR generates a molecular fingerprint by analyzing the infrared absorption spectra, and identifying functional groups within the sample. Meanwhile, NMR provides detailed insights into the molecular structure and composition by examining the interactions of nuclear spins within a magnetic field.

• Specific test

Our specific tests encompass a wide range of assessments to determine various properties and potential contaminants in the starch sample. These include:

• pH measurement: Using pH meters to assess the acidity or alkalinity of the sample.
• Sulfur dioxide content: Quantified through methods like ion chromatography to ensure the sample meets safety standards.
• Oxide levels: Analyzed using techniques like inductively coupled plasma optical emission spectrometry (ICP-OES) for precise measurement.
• 1,2-Propanediol concentration: Determined through gas chromatography (GC) to ensure no excessive residues.
• Loss on drying: Measured by heating the sample to a specified temperature and determining weight loss, which indicates moisture content.
• Residue on ignition: This involves incinerating the sample and measuring the remaining inorganic residue, ensuring the purity of the starch.
• Iron salt content: Analyzed using atomic absorption spectroscopy (AAS) or ICP-OES.
• Heavy metals presence: Determined through techniques such as inductively coupled plasma mass spectrometry (ICP-MS) for detecting trace metal contaminants.
• Arsenic salt levels: Specifically measured using ICP-MS due to its sensitivity and accuracy.
• Microbial limit: Assessed through microbial enumeration tests to ensure the sample is free from harmful microorganisms.
• Content test

Our content test is designed to quantify the amount of pregelatinized hydroxypropyl starch present in the sample. This typically involves high-performance liquid chromatography (HPLC) or other suitable quantitative methods to provide an accurate measurement of starch concentration. Based on our powerful Pharmaceutical and Biological Analysis Service, clients can find the most suitable service for their research needs.

Applications

• Our analysis service ensures the optimization of tablet formulations by providing crucial data on binding properties and controlled release mechanisms.
• Our analysis service helps in evaluating disintegration rates, which is vital for the effectiveness of orally administered medications.
• Our analysis service supports the development of innovative drug delivery systems by understanding the interaction between pregelatinized hydroxypropyl starch and active pharmaceutical ingredients.

Advantages

• Our analysis service ensures precise identification of pregelatinized hydroxypropyl starch, guaranteeing the authenticity and quality of the product.
• With state-of-the-art techniques and experienced analysts, we deliver reliable and consistent test results, providing confidence in the quality and performance of the analyzed starch.
• Our service can be tailored to meet specific customer requirements, accommodating unique testing needs and providing personalized solutions for different industries and applications.

At CD BioGlyco, our pregelatinized hydroxypropyl starch analysis service adheres to related requirements, ensuring the analyzed starch meets the requirements for pharmaceutical, food, and cosmetic applications. Please feel free to contact us for more information!