Pregnane X receptor inhibitor Meclizine 2HCl, Purity ≥98%

Synonym: 1104-22-9; Pregnane X receptor inhibitor; Meclozine

MDL: MFCD00058199
CAS Number: 1104-22-9
Compound CID: 64713

Product Size

10 g; 25 g; 50 g; 100 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Meclizine 2HCl, soluble in warmed DMSO and insoluble in water and ethanol, blocks the pregnane X receptor, a nuclear receptor involved in the regulation of genes associated with drug metabolism and transport.

Molecular Weight

463.87

Molecular Formula

C₂₅H₂₉Cl₃N₂

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 4 mg/mL (8.62 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Meclizine 2HCl is employed in studying drug metabolism and protection against toxicology through modulation of nuclear receptors.