Pregnane X receptor inhibitor SR-12813, Purity ≥98%

Synonym: 126411-39-0; Pregnane X receptor inhibitor; SR 12813

MDL: MFCD00888473
CAS Number: 126411-39-0
Compound CID: 446313

Product Size

10 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SR-12813, soluble in DMSO and ethanol and insoluble in water, blocks the pregnane X receptor, a nuclear receptor involved in the regulation of genes associated with drug metabolism and transport. It targets HMG-CoA reductase and pregnane X receptor.

Molecular Weight

504.54

Molecular Formula

C₂₄H₄₂O₇P₂

Targets

HMG-CoA reductase: 850 nM; Pregnane X receptor

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 97 mg/mL (192.25 mM); Water: Insoluble; Ethanol: 97 mg/mL (192.25 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

SR-12813 aids in research on pregnane X receptor roles in drug interactions and metabolic regulation.