PRMT inhibitor AMI-1, Purity ≥98%

Synonym: 20324-87-2; AMI 1; AMI1; AMI-1 disodium salt; Protein arginine methyltransferase inhibitor

CAS Number: 20324-87-2
Compound CID: 88489

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AMI-1, soluble in warmed DMSO and water and insoluble in ethanol, inhibits enzymes that methylate arginine residues in proteins, impacting signaling pathways and gene regulation. It targets human PRMT1, and yeast Hmt1p.

Molecular Weight

548.45

Molecular Formula

C₂₁H₁₄N₂Na₂O₉S₂

Targets

Human PRMT1: 8.8 μM; yeast Hmt1p: 3 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 89 mg/mL (162.27 mM); Water: 9 mg/mL (16.41 mM); Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AMI-1 can be used to inhibit histone methyltransferases for epigenetic research.

Storage

Store at -20ºC.