PRMT inhibitor EPZ020411 hydrochloride, Purity ≥98%

Synonym: 2070015-25-5; EPZ-020411; EPZ 020411; Protein arginine methyltransferase inhibitor

CAS Number: 2070015-25-5
Compound CID: 119081410

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

EPZ020411 hydrochloride, soluble in DMSO, water and ethanol, inhibits enzymes that methylate arginine residues in proteins, impacting signaling pathways and gene regulation. It targets PRMT1, PRMT6, and PRMT8.

Molecular Weight

479.06

Molecular Formula

C₂₅H₃₉ClN₄O₃

Targets

PRMT1: 0.119 μM; PRMT6: 0.01 μM; PRMT8: 0.223 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 86 mg/mL (166.81 mM); Water: 70 mg/mL (135.78 mM); Ethanol: 86 mg/mL (166.81 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

EPZ020411 hydrochloride can be used to inhibit G9a/GLP histone methyltransferase in epigenomics.

Storage

Store at -20ºC.