Properties
Description
GSK591, soluble in DMSO and ethanol and insoluble in water, inhibits enzymes that methylate arginine residues in proteins, impacting signaling pathways and gene regulation. It targets PRMT5.
Molecular Formula
C22H28N4O2
Solubility
DMSO: 75 mg/mL (197.11 mM); Water: Insoluble; Ethanol: 75 mg/mL (197.11 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
GSK591 can be used to study the inhibition of PRMT5, a protein arginine methyltransferase involved in gene expression and cellular proliferation.