PRMT inhibitor MS023, Purity ≥98%

Synonym: 1831110-54-3; MS-023; MS 023; Protein arginine methyltransferase inhibitor

CAS Number: 1831110-54-3
Compound CID: 92136227

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

MS023, soluble in DMSO and ethanol and insoluble in water, inhibits enzymes that methylate arginine residues in proteins, impacting signaling pathways and gene regulation. It targets PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8.

Molecular Weight

287.4

Molecular Formula

C₁₇H₂₅N₃O

Targets

PRMT1: 30 nM; PRMT3: 119 nM; PRMT4: 83 nM; PRMT6: 4 nM; PRMT8: 5 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 50 mg/mL (173.96 mM); Water: Insoluble; Ethanol: 50 mg/mL (173.96 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

MS023 can be used to study the inhibition of type I protein arginine methyltransferases (PRMTs) involved in multiple cellular processes.