Properties
Description
MS023, soluble in DMSO and ethanol and insoluble in water, inhibits enzymes that methylate arginine residues in proteins, impacting signaling pathways and gene regulation. It targets PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8.
Molecular Formula
C17H25N3O
Targets
PRMT1: 30 nM; PRMT3: 119 nM; PRMT4: 83 nM; PRMT6: 4 nM; PRMT8: 5 nM
Solubility
DMSO: 50 mg/mL (173.96 mM); Water: Insoluble; Ethanol: 50 mg/mL (173.96 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
MS023 can be used to study the inhibition of type I protein arginine methyltransferases (PRMTs) involved in multiple cellular processes.
