PRMT inhibitor SGC 707, Purity ≥98%

Synonym: 1687736-54-4; SGC707; SGC-707; Protein arginine methyltransferase inhibitor

CAS Number: 1687736-54-4
Compound CID: 90642938

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SGC 707, soluble in DMSO and warmed ethanol and insoluble in water, inhibits enzymes that methylate arginine residues in proteins, impacting signaling pathways and gene regulation. It targets PRMT3 and PRMT3.

Molecular Weight

298.3

Molecular Formula

C₁₆H₁₈N₄O₂

Targets

PRMT3: 31 nM; PRMT3: 53 nM (Kd)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 51 mg/mL (170.95 mM); Water: Insoluble; Warmed ethanol: 51 mg/mL (170.95 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

SGC 707 can be used to study the selective inhibition of the protein arginine methyltransferase CARM1/PRMT4.

Storage

Store at -20ºC.