PROTAC MDM2 degrader-2, Purity ≥98%

Synonym: 2249944-99-6; PROTAC MDM2 Degrader-2; AKOS040743841; MS-32149; HY-128841; CS-0100639; 2-[4-[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]-2-oxopiperazin-1-yl]-N-[2-[2-[2-[[2-[4-[(4R,5S)-4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]-2-oxopiperazin-1-yl]acetyl]amino]ethoxy]ethoxy]ethyl]acetamide; MDM2 inhibitor

CAS Number: 2249944-99-6
Compound CID: 138911384

Product Size

1 mg; 2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

MSDS

Properties

Description

PROTAC MDM2 degrader-2 prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells.

Molecular Weight

1391.22

Molecular Formula

C₇₀H₇₆Cl₄N₁₀O₁₂

Form

Lyophilized powder

Purity

Identity

Confirmed by NMR/HPLC/MS.

Applications

PROTAC MDM2 degrader-2 can be explored for its efficacy in selectively degrading MDM2, thereby stabilizing p53 and influencing cancer cell fate.