Properties
Description
AM 114 interferes with the proteasome’s ability to degrade proteins, thereby disrupting cellular processes in cancer cells, particularly multiple myeloma.
Molecular Formula
C20H21B2NO5
Identity
Confirmed by NMR/HPLC/MS.
Applications
AM 114 is used to study the ubiquitin-proteasome pathway by inhibiting the degradation of proteins marked for destruction, thus affecting protein homeostasis within cells.