Properties
Description
Bortezomib, soluble in DMSO and insoluble in ethanol and water, interferes with the proteasome’s ability to degrade proteins, thereby disrupting cellular processes in cancer cells, particularly multiple myeloma. It targets 20S proteasome.
Molecular Formula
C19H25BN4O4
Targets
20S proteasome: 0.6 nM (Ki)
Solubility
DMSO: 66 mg/mL (171.77 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Bortezomib is a proteasome inhibitor used to investigate protein degradation pathways and their therapeutic potential in cancer treatment, especially multiple myeloma.
