Proteasome inhibitor CEP-18770, Purity ≥98%

Synonym: 847499-27-8; Proteasome inhibitor; CEP18770

CAS Number: 847499-27-8
Compound CID: 24800541

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CEP-18770, soluble in DMSO and ethanol and insoluble in water, interferes with the proteasome’s ability to degrade proteins, thereby disrupting cellular processes in cancer cells, particularly multiple myeloma. It targets Chymotrypsin-like proteasome.

Molecular Weight

413.3

Molecular Formula

C₂₁H₂₈BN₃O₅

Targets

Chymotrypsin-like proteasome: 3.8 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 73 mg/mL (176.63 mM); Water: Insoluble; Ethanol: 73 mg/mL (176.63 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

CEP-18770 is investigated for its potential to inhibit proteasomes, focusing on cancer research such as multiple myeloma treatment.