Properties
Description
(R)-MG-132, soluble in DMSO and ethanol and insoluble in water, interferes with the proteasome’s ability to degrade proteins, thereby disrupting cellular processes in cancer cells, particularly multiple myeloma.
Molecular Formula
C26H41N3O5
Solubility
DMSO: 77 mg/mL (161.89 mM); Water: Insoluble; Ethanol: 22 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
(R)-MG-132 is a proteasome inhibitor employed to investigate proteasome function and ubiquitin-proteasome pathway in cellular processes.
